Registration Dossier
Registration Dossier
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EC number: 219-292-8 | CAS number: 2403-89-6
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Acute toxicity: via oral route
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed
- Dose descriptor:
- LD50
- Value:
- 1 285 mg/kg bw
Acute toxicity: via inhalation route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Acute toxicity: via dermal route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Additional information
Justification for classification or non-classification
With an LD 50 (oral, rat) of 1285 mg/kg this substance must be classified for Acute Toxicity Category 4 with GHS pictogram exclamation mark (GHS07), signal word Warning and H302: Harmful if swallowed.
This level of oral toxicity (rat) is supported by the LD50 (oral, rat) as mentioned in the OECD SIDS for the analogue substance 2,2’6,6’-TETRAMETHYLPIPERIDIN-4-OL (CAS 2403 -88 -5) which is missing the CH3-group on the nitrogen atom, and as measured by OECD TG401: 1482 mg/kg (male) and 1564 mg/kg (female). This OECD SIDS has been attached to the IUCLID dossier.
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