Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
in vivo mammalian germ cell study: gene mutation
Remarks:
Type of genotoxicity: gene mutation
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: secondary source from the IUCLID dataset.

Data source

Reference
Reference Type:
secondary source
Title:
IUCLID dataset
Author:
WP Mannheim GmbH
Year:
1985
Bibliographic source:
substance 81-84-5

Materials and methods

Principles of method if other than guideline:
no data
GLP compliance:
not specified
Remarks:
secondary source
Type of assay:
micronucleus assay

Test material

Constituent 1
Chemical structure
Reference substance name:
Naphthalene-1,8-dicarboxylic anhydride
EC Number:
201-380-2
EC Name:
Naphthalene-1,8-dicarboxylic anhydride
Cas Number:
81-84-5
Molecular formula:
C12H6O3
IUPAC Name:
3-oxatricyclo[7.3.1.0⁵,¹³]trideca-1(13),5,7,9,11-pentaene-2,4-dione
Details on test material:
same with section 1.1-1.4

Test animals

Species:
other: no data
Strain:
not specified
Sex:
not specified

Administration / exposure

Route of administration:
other: no data
Vehicle:
no data

Results and discussion

Test results
Sex:
not specified
Genotoxicity:
negative

Applicant's summary and conclusion