Registration Dossier

Administrative data

Endpoint:
skin irritation: in vivo
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1960

Materials and methods

Test guideline
Qualifier:
equivalent or similar to
Guideline:
EU Method B.4 (Acute Toxicity: Dermal Irritation / Corrosion)
Deviations:
yes
Remarks:
8-hour exposure of whole body except head
GLP compliance:
no

Test material

Reference
Name:
Unnamed
Type:
Constituent

Test animals

Species:
rabbit

Test system

Duration of treatment / exposure:
8 hours

Results and discussion

In vivo

Results
Irritation parameter:
overall irritation score
Remarks:
0
Time point:
other: 0
Score:
0
Max. score:
0
Reversibility:
other: no irritation occured

Applicant's summary and conclusion

Interpretation of results:
not irritating
Remarks:
Migrated information Criteria used for interpretation of results: EU
Executive summary:

During 8-hour exposure of male albino rabbits to cyanogen concentrations up to 10,000 ppm, no signs of irritation occured.