Registration Dossier

Administrative data

Endpoint:
activated sludge nitrification inhibition testing
Type of information:
migrated information: read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Read-across data from reputable review.

Data source

Reference
Reference Type:
review article or handbook
Title:
Cyanides of Hydrogen, Sodium and Potassium, and Acetone Cyanohydrin (CAS No. 74-90-8, 143-33-9, 151-50-8 and 75-86-5)
Author:
JACC
Year:
2007
Bibliographic source:
JACC, Cyanides of Hydrogen, Sodium and Potassium, and Acetone Cyanohydrin (CAS No. 74-90-8, 143-33-9, 151-50-8 and 75-86-5), 2007

Materials and methods

Test guideline
Qualifier:
equivalent or similar to
Guideline:
ISO 9509 (Toxicity test for assessing the inhibition of nitrification of activated sludge microorganisms)
Deviations:
not specified
GLP compliance:
not specified

Test material

Reference
Name:
Unnamed
Type:
Constituent

Sampling and analysis

Analytical monitoring:
not specified

Test organisms

Test organisms (species):
activated sludge

Study design

Test type:
not specified

Results and discussion

Effect concentrations
Duration:
6 h
Dose descriptor:
EC50
Effect conc.:
4.9 mg/L

Applicant's summary and conclusion

Validity criteria fulfilled:
yes
Conclusions:
6-hr EC50 for activated sludge exposed to cyanide was 4.9 mg/L.