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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Toxicity to birds

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Administrative data

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Description of key information

ATMP-xNH4 will dissociate into ATMP and ammonia in the route of administration in oral exposures (food), therefore the two substances must be assessed separately.


A NOAEL of 886 mg/kg bw/day has been determined for ammonium sulfate in a 13-week repeated-dose feeding study with male rats (diarrhea). The value is equivalent to 228 mg/kg bw/day (ammonia).


There are no data available with ATMP-xNH4, therefore data have been read-across from ATMP-H.

A short-term (14-day) LC50 value of >565 mg active acid/kg bw has been determined for the effects of ATMP-H on mortality of Anas platyrhynchos.

A short-term (14-day) LD50 value of >2510 mg/kg bw/day, equivalent to >565 mg active acid/kg bw/day, has been determined for the effects of ATMP-H on mortality of Colinus virginianus.

Key value for chemical safety assessment

Additional information

ATMP-xNH4 will dissociate into ATMP and ammonia when it is released into aquatic and terrestrial food chains where water is present. ATMP and ammonia will therefore be treated separately for the purposes of deriving PNECoral.

Two short-term toxicity tests (14-day) are available with Anas platyrhynchos and Colinus virginianus during which no mortalities were recorded up to the highest treatment. Therefore the EC50 values were >565 mg active acid/kg bw. However neither have been selected as key since ECHA (2008, Guidance on information requirements and chemical safety assessment Part B: Hazard Assessment May 2008, version 1.1) reads: "due to poor correlation between short- and long-term effects, only long term studies are considered suitable for CSA purposes".

PNECoral is not calculated for ATMP or ammonia because they do not have the potential to bioaccumulate.