Registration Dossier

Diss Factsheets

Ecotoxicological information

Long-term toxicity to fish

Currently viewing:

Administrative data

Link to relevant study record(s)

Description of key information

There are no test data for the substance. A 60-d NOEC of 23 mg/L (as active acid) has however been determined for the effects of ATMP acid (CAS 6419-19-8) on growth of the freshwater fish Oncorhynchus mykiss.

Key value for chemical safety assessment

Additional information

ATMP-xNH4 will dissociate when it is released into aqueous environments to yield ATMP and ammonia.

The assessment of long-term toxicity of the substance to fish will, for the purposes of hazard classification and in the absence of test data, be based on treating the substance as a preparation. Test data do not indicate that ATMP acid is toxic to fish following long-term exposure. The un-ionised ammonia moiety is however known to be toxic to aquatic organisms and concentration limits, as stipulated in the Annex I (DSD)/Annex VI (CLP) entry for ammonia, will be applied in order to derive a hazard classification for ATMP-xNH4.

ATMP and ammonia will also be treated separately for the purposes of deriving PNECs for the aquatic compartment. A PNECaquatic for ammonia has already been derived by the UK Environment Agency for the purpose of setting an Environmental Quality Standard (EQS) under Annex VIII of the Water Framework Directive (WFD). The relevant data are presented in section 7.6 of the CSR. This PNEC is also considered to be adequate for the purpose of risk characterisation of ammonia present in ATMP-xNH4. A PNEC for ATMP will be determined using test data for the substance.

Categories Display