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EC number: 251-908-0 | CAS number: 34274-28-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
There are no test data for the substance. A 96 h LC50 value of 160 mg/L (as active acid) has however been determined for the effects of ATMP acid (CAS 6419-19-8) on mortality of the freshwater fish Salmo gairdneri (now known as Onychorhynchus mykiss). A 96 h LC50 value of >282 mg/L (as active acid) has also been determined for the effects of ATMP on mortality of the marine fish Cyprinodon variegatus. The result was obtained in a test conducted with ATMP 5Na salt (CAS 2235-43-0) and the result has been expressed relative to the concentration of ATMP acid.
Key value for chemical safety assessment
Additional information
ATMP-xNH4 will dissociate when it is released into aqueous environments to yield ATMP and ammonia.
The assessment of short-term toxicity of the substance to fish and the resulting hazard classification are therefore, in the absence of test data for the substance, based on treating the substance as a preparation. Test data do not indicate that ATMP acid is toxic to fish following short-term exposure. The un-ionised ammonia moiety is however known to be toxic to aquatic organisms and concentration limits, as stipulated in the Annex I (DSD)/Annex VI (CLP) entry for ammonia, will be applied in order to derive a hazard classification for ATMP-xNH4.
ATMP and ammonia will also be treated separately for the purposes of deriving PNECs for the aquatic compartment. A PNECaquatic for ammonia has already been derived by the UK Environment Agency for the purpose of setting an Environmental Quality Standard (EQS) under Annex VIII of the Water Framework Directive (WFD). The relevant data are presented in section 7.6 of the CSR. This PNEC is also considered to be adequate for the purpose of risk characterisation of ammonia present in ATMP-xNH4. A PNEC for ATMP will be determined using test data for the substance.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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