Registration Dossier
Registration Dossier
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EC number: 208-793-7 | CAS number: 541-85-5
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
A toxicity threshold (TT) concentration for Scenedesmus quadricauda (green algea) for the read across substance (CASNr: 106-68-3) was determined for at 53 mg/l in a the cell multiplication inhibition test.
A toxicity threshold (TT) concentration for Microcystis aeruginosa (blue algea) for the read across substance (CASNr: 106-68-3) was determined at 40 mg/l in a cell multiplication inhibition test.
The results were confirmed by an estimation of EC50 (96 h, green algae) for 5-methylheptan-3-one (CASNr: 541-85-5) using Ecosar ( 35.2 mg/l).
Key value for chemical safety assessment
- EC10 or NOEC for freshwater algae:
- 40 mg/L
Additional information
Toxicity threshold concentrations after 8 days, representing a worst-case EC10 value, for the read across substance (CASNr: 106-68-3) were determined for Scenedesmus quadricauda (green algea) and Microcystis aeruginosa (blue algea). The EC50 for 5-methylheptan-3-one (CASNr: 541-85-5) after 96 h was estimated to be simiar (35.2 mg/l) using Ecosar. For the chemical safety assessment, the lowest measured EC10 for the read accross substance (CAS Nr: 106 -68-3) was selected and was, as a worst-case, treated as a EC50 for the substance of interest 5-methylheptan-3-one (CASNr: 541-85-5). Since all toxicity threshold values are above 1 mg/l and 5-methylheptan-3-one (CASNr: 541-85-5) is readily biodegradable, no classification is necessary due to toxicity to algae.
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