Registration Dossier
Registration Dossier
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EC number: 203-534-4 | CAS number: 107-94-8
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
ErC50: 45.3 mg/L
ErC10: 10.1 mg/L
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 45.3 mg/L
- EC10 or NOEC for freshwater algae:
- 10.1 mg/L
Additional information
For this endpoint, two studies are available: one Klimisch 1 study and one Klimisch 4 information.
In the Klimisch 1 GLP study from Aniol (2015) the toxicity 3-chloropropionic acid (purity 99.1%) to Desmodesmus subspicatus was determined in a static 72 -Hour Algal Growth Inhibition Test according to OECD 201. All validity critera were fulfilled. The nominal concentrations of the test item of Control, 3.07, 7.68, 19.2, 48.0 and 120 mg/L were tested in parallel with a control. Dose verification analysis was performed. The biological data were based on nominal concentrations.The growth of the control cultures fulfilled the validity criteria from OECD 201 (2006). The 72 -hour ErC10 and ErC50 are 10.1 and 45.3 mg 3-chloropropionic acid /L based on nominal concentrations. This information is considered to be relevant and reliable for the further risk assessment.
Supporting study:
A 7-day non-standard test with Scenedesmus subspicatus resulted in a EC3 (equivalent to NOEC) of 689 mg/L.
The test period was unusual and insufficient details are available to enable the test results to be fully evaluated. This study is not considered for the risk assessment.
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