Registration Dossier
Registration Dossier
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EC number: 278-077-7 | CAS number: 75128-73-3
Genetic toxicity: in vitro
Administrative data
- Endpoint:
- genetic toxicity in vitro
- Remarks:
- Type of genotoxicity: other: chromosome damage, genotoxicity and mutagenicity
- Type of information:
- (Q)SAR
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Justification for type of information:
- QSAR prediction: migrated from IUCLID 5.6
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 012
- Report date:
- 2012
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- Software used: DEREK Nexus, version 2.0.0, 2010 LHASA Ltd, Leeds, UK
- GLP compliance:
- no
- Type of assay:
- other: QSAR using Derek Nexus, version 2.0.0
Test material
- Reference substance name:
- 2-[(2-acetamido-6,9-dihydro-6-oxo-1H-purin-9-yl]methoxy]ethyl acetate
- EC Number:
- 278-077-7
- EC Name:
- 2-[(2-acetamido-6,9-dihydro-6-oxo-1H-purin-9-yl]methoxy]ethyl acetate
- Cas Number:
- 75128-73-3
- Molecular formula:
- C12H15N5O5
- IUPAC Name:
- 2-[(2-acetamido-6,9-dihydro-6-oxo-1H-purin-9-yl]methoxy]ethyl acetate
Constituent 1
Results and discussion
Test results
- Species / strain:
- not specified
- Metabolic activation:
- not applicable
- Genotoxicity:
- other: no alert
- Cytotoxicity / choice of top concentrations:
- not determined
- Additional information on results:
- No alert for chromosome damage, genotoxicity and mutagenicity of the 2-[(2-acetamido-6-oxo-1,6-dihydro-9H-purin-9-yl)methoxy]ethyl acetate was detected by DEREK Nexus version 2.0.0.
Applicant's summary and conclusion
- Conclusions:
- Interpretation of results (migrated information):
other: no alert
No alert for chromosome damage, genotoxicity and mutagenicity of the substance 2-[(2-acetamido-6-oxo-1,6-dihydro-9H-purin-9-yl)methoxy]ethyl acetate was detected by DEREK Nexus version 2.0.0.
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