Registration Dossier
Registration Dossier
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EC number: 701-004-1 | CAS number: -
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Acute toxicity: via oral route
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed
Acute toxicity: via inhalation route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Acute toxicity: via dermal route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Additional information
There is no data for CAS # 102242 -57 -9 available but for the single components which can be used for read across:
Acute toxicity oral
Benzene (ca. 50 % in the substance):
An oral LD50 value in rats of > 2000 mg/kg is derived from two studies (Kimura et al, 1971; Withey and Hall, 1975). Although little information on clinical signs is included in these publications the EU RAR (2008) stated "depending on the dose the main clinical signs are sedation and hind-limb paralysis".
Cyclopentene (and 1 -methylcyclopentene) (together ca. 17 % in the substance):
The oral LD50 for cyclopentene was 1656 mg/kg in male rats (Smyth H.F. et.al. 1962 and 1969). Based on structural similarities it can be assumed that the oral LD50 for 1 -methylcyclopentene will also be in the range of 300 to 2000 mg/kg.
Based on a weight of evidence approach the oral LD50 of the substance will be in the range of > 300 and < 2000 mg/kg.
Justification for classification or non-classification
Based on the available data an R22 according to DSD-DPD and the Acute oral Cat. 4 according to CLP is warranted.
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