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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Key value for chemical safety assessment

Additional information

Di-EPh was assessed for genotoxicity in in vitro bacterial mutagenicity, chromosome aberration and mammalian cell mutagenicity assays. Di-EPh was not mutagenic or clastogenic in any of the assays.

Short description of key information:
A bacterial mutagenicity, chromosome aberration and mammalian cell mutagenicity assay are available for Di-EPh. All studies are Klimisch reliability 1, OECD guideline studies. In addition, in vivo and in vitro genotoxicity studies on the structural analogue E-Ph are also available. These data are included for information only since the studies on Di-EPh are sufficient to meet the data requirements.

Endpoint Conclusion: No adverse effect observed (negative)

Justification for classification or non-classification

No classification is required due to the absence of genotoxicity and clastogenicity in the available OECD guideline studies.