Registration Dossier
Registration Dossier
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Diss Factsheets
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EC number: 203-227-5 | CAS number: 104-68-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
PBT assessment
Administrative data
PBT assessment: overall result
- PBT status:
- the substance is not PBT / vPvB
- Justification:
For the ecotoxicological studies:
Persistence assessment: The test substance does not meet the criteria of P or vP because it is readily biodegradable. In a standard biodegradation screening test based on OECD guideline 301F, biodegradation of Di-EPh was observed. The extent of DiEPh biodegradation based on BOD, CO2evolution, and DOC removal reached 100.5 ± 1.1%, 87.0 ± 0.3%, and 95.3 ± 0.6%, (mean ± 1 SD), respectively, at the end of the 28-day test. Thus, the biodegradation of DiEPh achieved both the pass level and 10-day window criteria for classification as readily biodegradable in the Manometric Respirometry Test.
Bioaccumulation assessment: The test substance does not meet the criteria of B and vB. The substance has a low potential to bioaccumulate because of its low log Pow value (0.8). Screening criteria for bioaccumulation states that test substances with log Pow values ≤ 4.5 are not B and not vB.
Toxicity Assessment: The 96-hour LC50 for fathead minnow (Pimephales promelas) was 432 mg/L.
The 48-hour EC50 for freshwater invertebrate (Daphnia magna) was 906 mg/L. The 72-hour ErC50 (based on growth rate) for freshwater algae (Pseudokirchnerella subcapitata) was determined to be 393 mg/L. Because these aquatic toxicity endpoints are more than 3000-fold higher than the 0.1 mg/L threshold for toxicity (T), the test substance is not T.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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