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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Eye irritation

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Administrative data

Endpoint:
eye irritation: in vivo
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: 2a: Data from international report

Data source

Reference
Reference Type:
review article or handbook
Title:
SIDS INITIAL ASSESSMENT PROFILE
Author:
OECD
Year:
2011
Bibliographic source:
UNEP Publications
Report date:
2011

Materials and methods

Test guideline
Qualifier:
no guideline available
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
Thiophene
EC Number:
203-729-4
EC Name:
Thiophene
Cas Number:
110-02-1
Molecular formula:
C4H4S
IUPAC Name:
thiophene

Test animals / tissue source

Species:
rabbit

Results and discussion

Applicant's summary and conclusion

Conclusions:
Thiophene caused eye irritation in rabbits.