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Ecotoxicological information

Long-term toxicity to aquatic invertebrates

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Reference
Endpoint:
long-term toxicity to aquatic invertebrates
Type of information:
calculation (if not (Q)SAR)
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
accepted calculation method
Justification for type of information:
Data is from ECOSAR version 1.11
Qualifier:
according to
Guideline:
other: Modeling database
Principles of method if other than guideline:
Long term toxicity of test chemical were estimated for exposure period of 21 days.
GLP compliance:
no
Vehicle:
not specified
Test organisms (species):
Daphnia magna
Test type:
not specified
Water media type:
not specified
Reference substance (positive control):
not specified
Key result
Duration:
21 d
Dose descriptor:
NOEC
Effect conc.:
0 mg/L
Nominal / measured:
estimated
Conc. based on:
test mat.
Basis for effect:
immobilisation
Remarks on result:
other: ECOSAR v1.11
Validity criteria fulfilled:
not specified
Conclusions:
On the basis of no effects observed in a freshwater system, the NOEC value for the substance is estimated to be 1.79e-005 mg/l for aquatic invertebrate for 21 days of exposure duration.
Executive summary:

Based on the prediction done using ECOSAR version 1.1, the long term toxicity on aquatic invertebrate was predicted for test substance . On the basis of effects observed in a freshwater system, the NOEC value for the test substance is estimated to be 1.79e-005 mg/l for aquatic invertebrate for 21 days of exposure, Based on the NOEC value it can be concluded that the test chemical can be considered as toxic to aquatic invertebrate at environmentally relevant concentrations and can be considered aquatic chronic 1 as per the CLP classification criteria.

Description of key information

Long term toxicity to aquatic invertebrate:

Based on the prediction done using ECOSAR version 1.1, the long term toxicity on aquatic invertebrate was predicted for test substance . On the basis of effects observed in a static freshwater system, the NOEC value for the test substance is estimated to be1.79e-005mg/l for aquatic invertebrate for 21 days of exposure, Based on the NOEC value it can be concluded that the test chemical can be considered as toxic to aquatic invertebrate at environmentally relevant concentrations and can be considered aquatic chronic 1 as per the CLP classification criteria.

Key value for chemical safety assessment

EC10, LC10 or NOEC for freshwater invertebrates:
0.002 mg/L

Additional information

Long term toxicity to aquatic invertebrate:

Based on the prediction done using ECOSAR version 1.1, the long term toxicity on aquatic invertebrate was predicted for test substance . On the basis of effects observed in a static freshwater system, the NOEC value for the test substance is estimated to be1.79e-005mg/l for aquatic invertebrate for 21 days of exposure, Based on the NOEC value it can be concluded that the test chemical can be considered as toxic to aquatic invertebrate at environmentally relevant concentrations and can be considered aquatic chronic 1 as per the CLP classification criteria.