Tetrahydrofuran-borane

Endpoint summary

Additional information

Tetrahydrofuran-borane is known to readily hydrolize liberating hydrogen, tetrahydrofuran (CAS 109-99-9) and boric acid (CAS 10043-35-3). For both hydrolysis products relevant aquatic toxicity data was gathered from the ECHA dissemination dossier (d.d. 2014 -04 -24) and tabulated below.

Aquatic toxicity data for tetrahydrofuran:

Study	Species	Endpoint	Effect value
Fish acute toxicity	P. promelas	96-h LC50	2160 mg/L
Fish chronic toxicity	P. promelas	33 -d NOEC	216 mg/L
Aquatic invertebrates acute toxicity	D. magna	48-h LC50	3485 mg/L*
Aquatic invertebrates chronic toxicity	No information available	-	-
Algae acute	No information available	-	-
Algae chronic	S. quadricauda	8 -d EC3**	3700 mg/L

* effect value expressed as parts per milion (ppm).

** endpoint expressed as "toxicity threshold concentration (equivalent to EC3)"

Aquatic toxicity data for boric acid:

Study	Species	Endpoint	Effect value
Fish acute toxicity	L. limanda (saltwater)	96-h LC50	74 mg/L*
Fish chronic toxicity	I. punctatus	9-d LC10	3.5 mg/L**
Aquatic invertebrates acute toxicity	H. azteca	96-h LC50	64 mg/L***
Aquatic invertebrates chronic toxicity	D. magna	21-d NOEC	6 mg/L****
Algae acute	S. capricornutum	72-h EC50	52.4 mg/L *****
Algae chronic	S. capricornutum	72-h NOEC	17.5 mg/L *****

* lowest effect concentration of two WoE endpoints for a boric acid (82%) and disodium tetraborate decahydrate (18%) mixture and for disodium tetraborate, anhydrous.

** lowest effect value of a total of 11 WoE endpoints for both boric acid and various boron/borate species.

*** lowest effect concentration of a total of 23 WoE endpoints for both boric acid and various boron/borate species.

**** lowest effect concentration of a total of 10 WoE endpoints for both boric acid and various boron/borate species.

***** lowest effect concentrations from one of two WoE endpoints.