Registration Dossier

Ecotoxicological information

Endpoint summary

Administrative data

Description of key information

Additional information

Tetrahydrofuran-borane is known to readily hydrolize liberating hydrogen, tetrahydrofuran (CAS 109-99-9) and boric acid (CAS 10043-35-3). For both hydrolysis products relevant aquatic toxicity data was gathered from the ECHA dissemination dossier (d.d. 2014 -04 -24) and tabulated below.

Aquatic toxicity data for tetrahydrofuran:

Study

Species

Endpoint

Effect value

Fish acute toxicity

P. promelas

96-h LC50

2160 mg/L

Fish chronic toxicity

P. promelas

33 -d NOEC

216 mg/L

Aquatic invertebrates acute toxicity

D. magna

48-h LC50

3485 mg/L*

Aquatic invertebrates chronic toxicity

No information available

-

-

Algae acute

No information available

-

-

Algae chronic

S. quadricauda

8 -d EC3**

3700 mg/L

* effect value expressed as parts per milion (ppm).

** endpoint expressed as "toxicity threshold concentration (equivalent to EC3)"

Aquatic toxicity data for boric acid:

Study

Species

Endpoint

Effect value

Fish acute toxicity

L. limanda (saltwater)

96-h LC50

74 mg/L*

Fish chronic toxicity

I. punctatus

9-d LC10

3.5 mg/L**

Aquatic invertebrates acute toxicity

H. azteca

96-h LC50

64 mg/L***

Aquatic invertebrates chronic toxicity

D. magna

21-d NOEC

6 mg/L****

Algae acute

S. capricornutum

72-h EC50

52.4 mg/L *****

Algae chronic

S. capricornutum 

72-h NOEC

17.5 mg/L *****

* lowest effect concentration of two WoE endpoints for a boric acid (82%) and disodium tetraborate decahydrate (18%) mixture and for disodium tetraborate, anhydrous.

** lowest effect value of a total of 11 WoE endpoints for both boric acid and various boron/borate species.

*** lowest effect concentration of a total of 23 WoE endpoints for both boric acid and various boron/borate species.

**** lowest effect concentration of a total of 10 WoE endpoints for both boric acid and various boron/borate species.

***** lowest effect concentrations from one of two WoE endpoints.