Registration Dossier
Registration Dossier
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EC number: 203-556-4 | CAS number: 108-16-7
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
1-(dimethylamino)propan-2-ol is acutely harmful to aquatic organisms
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 79 mg/L
Additional information
An EC50 of 79 mg/L was determined in a study testing the toxicity of 1 -(dimethylamino)propan-2 -ol to Daphnia magna conducted according to guideline DIN 38412, part L11 (BASF AG 1989). The effect of the substance on the mobility of D. magna is probably in part due to pH changes caused by the substance. In a parallel test with a neutralised sample of the highest concentration (580 mg/L) the toxicity of the test item was reduced as after 48 h the immobilisation was 50% compared to 100% in the not-neutralised sample. Moreover, the effects were delayed in time as only 5% of the daphnids were immobilised in the neutralised 580 mg/L sample while in the not-neutralised sample all daphnids were immobilised already after 3 h. The test item concentrations were not analytically verified, but are assumed to be stable.
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