Registration Dossier

Environmental fate & pathways

Adsorption / desorption

Currently viewing:

Administrative data

Link to relevant study record(s)

Reference
Endpoint:
adsorption / desorption: screening
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data
Justification for type of information:
Data is from HSDB and PubChem authoritative database
Qualifier:
according to
Guideline:
other: as mentioned below
Principles of method if other than guideline:
Soil adsorption coefficient (Koc) of test chemical was estimated using a logKow and a regression derived equation.
GLP compliance:
not specified
Type of method:
other: no data available
Media:
soil
Radiolabelling:
not specified
Analytical monitoring:
not specified
Computational methods:
- Other: Koc value of test chemical was estimated using a logKow of 1.83 and a regression derived equation.
Key result
Type:
Koc
Value:
74 dimensionless
Remarks on result:
other: Log Koc= 1.86
Transformation products:
not specified

According to a classification scheme, the estimated Koc value suggests that test chemical is expected to have high mobility in soil.

Validity criteria fulfilled:
not specified
Conclusions:
The adsorption coefficient (Koc) value of test chemical was estimated to be 74 calculated using a logKow and a regression derived equation.
Executive summary:

Adsorption study was conducted for estimating the adsorption coefficient (Koc) value of test chemical. The adsorption coefficient (Koc) value was calculated using a logKow of 1.83 and a regression derived equation. The adsorption coefficient (Koc) value of test chemical was estimated to be 74 (Log Koc = 1.86). This Koc value indicates that the test chemical has a low sorption to soil and sediment and therefore have moderate migration potential to ground water.

Description of key information

Adsorption study was conducted for estimating the adsorption coefficient (Koc) value of test chemical (authoritative databases, 2017). The adsorption coefficient (Koc) value was calculated using a logKow of 1.83 and a regression derived equation. The adsorption coefficient (Koc) value of test chemical was estimated to be 74 (Log Koc = 1.86). This Koc value indicates that the test chemical has a low sorption to soil and sediment and therefore have moderate migration potential to ground water.

Key value for chemical safety assessment

Koc at 20 °C:
74

Additional information

Experimental study and various predicted data of the test chemical were reviewed for the adsorption end point which are summarized as below:

 

In an experimental key study from authoritative database (2017),adsorption experiment was conducted for estimating the adsorption coefficient (Koc) value of test chemical. The adsorption coefficient (Koc) value was calculated using a logKow of 1.83 and a regression derived equation. The adsorption coefficient (Koc) value of test chemical was estimated to be 74 (Log Koc = 1.86).

 

In a prediction done using the BCFBAF Programof Estimation Programs Interface was used to predict the soil adsorption coefficient i.e Koc value of test chemical. The soil adsorption coefficient i.e Koc value of test chemical was estimated to be 120 L/kg (log Koc=2.0791) by means of MCI method (at 25 deg C). This Koc value indicates that the test chemical has a low sorption to soil and sediment and therefore have moderate migration potential to ground water.

 

The Soil Adsorption Coefficient i.e Koc value of test chemical was estimated using Adsorption Coefficient module program as Koc 280 (logKoc = 2.4 ± 1.0) at pH range 1-14, respectively(ACD (Advanced Chemistry Development)/I-Lab predictive module, 2017)).

 

On the basis of above overall results for test chemical (from authoritative and modelling databases,2017), it can be concluded that the logKoc value of test chemicalranges from1.86– 2.4, indicating that the test chemical has a low sorption to soil and sediment and therefore have moderate migration potential to ground water.

 

Waiver statement

In accordance with column 2 of Annex IX of the REACH regulation,testing for this endpointis scientifically not necessary and does not need to be conducted since the test chemicalhas a low potential for adsorption based on low octanol water partition coefficient.