Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
carcinogenicity
Type of information:
(Q)SAR
Adequacy of study:
key study
Study period:
2010
Reliability:
2 (reliable with restrictions)
Justification for type of information:
QSAR prediction: migrated from IUCLID 5.6

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2010
Report date:
2010

Materials and methods

Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
In silico prediction using DEREK.
DEREK is a knowledge-based expert system designed to apply structure-activity relationships to compounds for which little or no data exists and hence to aid in the assessment of their potential toxicity. The DEREK knowledge base contains a large number of rules that associate a chemical structure with one or more toxicity end points. When a structural alert is identified a reasoning programme assigns a probability to the expression of toxicity by the test compound.
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
1H-indazole-3-carboxylic acid
EC Number:
224-794-5
EC Name:
1H-indazole-3-carboxylic acid
Cas Number:
4498-67-3
Molecular formula:
C8H6N2O2
IUPAC Name:
1H-indazole-3-carboxylic acid

Results and discussion

Any other information on results incl. tables

DEREK evaluation showed no alert for carcinogenicity effects.

Applicant's summary and conclusion

Conclusions:
DEREK evaluation showed no alert for carcinogenicity effects.