Registration Dossier
Registration Dossier
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EC number: 224-794-5 | CAS number: 4498-67-3
Skin irritation / corrosion
Administrative data
- Endpoint:
- skin irritation / corrosion
- Remarks:
- other: In silico prediction
- Type of information:
- (Q)SAR
- Adequacy of study:
- key study
- Study period:
- 2010
- Reliability:
- 2 (reliable with restrictions)
- Justification for type of information:
- QSAR prediction: migrated from IUCLID 5.6
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 010
- Report date:
- 2010
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- In silico prediction.
Tox Boxes 2.9 is the in house software for the prediction of basic toxicity endpoints in chemicals. Predictions are made analyzing the chemical structure and based upon large validated databases and QSAR models, in combination with expert knowledge of organic chemistry and toxicology. - GLP compliance:
- not specified
Test material
- Reference substance name:
- 1H-indazole-3-carboxylic acid
- EC Number:
- 224-794-5
- EC Name:
- 1H-indazole-3-carboxylic acid
- Cas Number:
- 4498-67-3
- Molecular formula:
- C8H6N2O2
- IUPAC Name:
- 1H-indazole-3-carboxylic acid
Constituent 1
Test animals
- Species:
- rabbit
Results and discussion
Any other information on results incl. tables
Skin irritation shows low probability of severe/moderate irritation value with low reliability index.
Applicant's summary and conclusion
- Interpretation of results:
- other: low alert
- Remarks:
- Criteria used for interpretation of results: expert judgment
- Conclusions:
- Skin irritation shows low probability of severe/moderate irritation value with low reliability index.
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