Registration Dossier

Administrative data

Endpoint:
skin irritation / corrosion
Remarks:
other: In silico prediction
Type of information:
(Q)SAR
Adequacy of study:
key study
Study period:
2010
Reliability:
2 (reliable with restrictions)
Justification for type of information:
QSAR prediction: migrated from IUCLID 5.6

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2010
Report Date:
2010

Materials and methods

Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
In silico prediction.
Tox Boxes 2.9 is the in house software for the prediction of basic toxicity endpoints in chemicals. Predictions are made analyzing the chemical structure and based upon large validated databases and QSAR models, in combination with expert knowledge of organic chemistry and toxicology.
GLP compliance:
not specified

Test material

Reference
Name:
Unnamed
Type:
Constituent

Test animals

Species:
rabbit

Results and discussion

Any other information on results incl. tables

Skin irritation shows low probability of severe/moderate irritation value with low reliability index.

Applicant's summary and conclusion

Interpretation of results:
other: low alert
Remarks:
Criteria used for interpretation of results: expert judgment
Conclusions:
Skin irritation shows low probability of severe/moderate irritation value with low reliability index.