Registration Dossier
Registration Dossier
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EC number: 224-794-5 | CAS number: 4498-67-3
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- (Q)SAR
- Adequacy of study:
- key study
- Study period:
- 2010
- Reliability:
- 2 (reliable with restrictions)
- Justification for type of information:
- QSAR prediction: migrated from IUCLID 5.6
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 010
- Report date:
- 2010
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- In silico prediction.
Tox Boxes 2.9 is the in house software for the prediction of basic toxicity endpoints in chemicals. Predictions are made analyzing the chemical structure and based upon large validated databases and QSAR models, in combination with expert knowledge of organic chemistry and toxicology. - GLP compliance:
- not specified
- Test type:
- other: in silico prediction
Test material
- Reference substance name:
- 1H-indazole-3-carboxylic acid
- EC Number:
- 224-794-5
- EC Name:
- 1H-indazole-3-carboxylic acid
- Cas Number:
- 4498-67-3
- Molecular formula:
- C8H6N2O2
- IUPAC Name:
- 1H-indazole-3-carboxylic acid
Constituent 1
Test animals
- Species:
- rat
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Route of administration:
- oral: unspecified
Results and discussion
Effect levels
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- 1 100 mg/kg bw
Any other information on results incl. tables
Acute toxicity shows values with moderate reliability index.
Applicant's summary and conclusion
- Interpretation of results:
- other: alert, moderate reliability index
- Remarks:
- Criteria used for interpretation of results: expert judgment
- Conclusions:
- Acute toxicity shows values with moderate reliability index.
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