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EC number: 610-288-5 | CAS number: 462-20-4
Vapour pressure
Administrative data
Link to relevant study record(s)
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 09.11.2000 - 29.11.2000
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.4 (Vapour Pressure)
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- effusion method: vapour pressure balance
- Key result
- Test no.:
- #1
- Temp.:
- 25 °C
- Vapour pressure:
- 0 Pa
- Conclusions:
- The Test material Dihydrolipoic Acid has been determined to have a vapour pressure of 9.9E-6 Pa at 25 °C using a vapour pressure balance.
- Executive summary:
A study (according to Method A.4 specified in Commission Directive 92/69/EEC) was performed to determine the vapour pressure of Dihydrolipoic Acid. In this study the test material has been determined to have a vapour pressure of 9.9E-6 Pa at 25 °C using a vapour pressure balance.
Reference
Plots of Log10 (Vapour pressure (Pa)) versus reciprocal temperature (1/T(K)) for Run 1-5 gave the following data using an unweighted least squares treatment:
Table 1: Statistical data of plots of Log10 (vapour pressure (Pa)) versus reciprocal temperature (1/T(K)).
|
Run 1 |
Run 2 |
Run 3 |
Run 4 |
Run 5 |
Slope |
-7611.688 |
-6900.364 |
-7862.595 |
-9022.029 |
-5813.245 |
Standard deviation in slope |
141.268 |
30.646 |
136.744 |
363.780 |
100.731 |
Intercept |
20.616 |
18.563 |
21.252 |
24.458 |
14.890 |
Standard deviation in intercept |
0.416 |
0.094 |
0.403 |
1.054 |
0.293 |
This data yield the folowing results:
Table 2: Results of the five runs (log10[Vp(25°C)]), mean and resulting vapour pressure.
Run |
Log10[Vp(25°C)] |
1 |
- 4.914 |
2 |
- 4.581 |
3 |
- 5.120 |
4 |
- 5.802 |
5 |
- 4.608 |
Mean Vapour Pressure |
- 5.005 9.9 x 10-6Pa |
The test material did not change in appearence under the conditons used in the determination.
Description of key information
The Test material Dihydrolipoic Acid has been determined to have a vapour pressure
of 9.9E-6 Pa at 25 °C using a vapour pressure balance.
Key value for chemical safety assessment
- Vapour pressure:
- 0 Pa
- at the temperature of:
- 25 °C
Additional information
A study (according to Method A.4 specified in Commission Directive 92/69/EEC) was performed to determine the vapour pressure of Dihydrolipoic Acid. In this study the test material has been determined to have a vapour pressure of 9.9E-6 Pa at 25 °C using a vapour pressure balance.
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