Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 614-452-7 | CAS number: 68410-23-1
Bioaccumulation: aquatic / sediment
Administrative data
Link to relevant study record(s)
Description of key information
The bioconcentration factor for the substance was estimated by QSAR to be 492 L/kg.
Key value for chemical safety assessment
- BCF (aquatic species):
- 492 L/kg ww
Additional information
Due to technical feasability issues an experimental value could not be determined for DimerFA PEPA PAA. Analytical methods of sufficient accuracy for testing concentrations of the substance in test media and biological material were not available. Further to this it is likely that a standard OECD 305 test would not be suitable for such a strongly sorbing substance.
A QSAR was conducted using BCFBAFv3.01 in order to calculate the bioconcentration factor from an estimated log Kow. The bioconcentration factor was estimated for both linear and cyclic forms of the representative substance.
The BCF was estimated to be 492 L/kg for the linear form and 70.8 L/kg for the cyclic form. This indicates that the bioaccumulation potential for this substance will be of a low to medium level. It is likely that the large molecular size will likely limit uptake of the substance by biological membranes. As such, this substance is not considered to be bioaccumulative.
For risk assessment purposes the larger value of 492 L/kg has been taken to provide a worst case scenario.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
