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The Volume of distribution is 0.13 L/kg.
Candesartan does not penetrate red blood cells.
Absolute bioavailability of candesartan from the administered prodrug, candesartan cilexetil, has been estimated to be about 15%.
During absorption from the gastrointestinal tract, candesartan cilexetil undergoes rapid and complete ester hydrolysis to form the active drug, candesartan.
Elimination of candesartan is primarily as unchanged drug in the urine and, by the biliary route, in the feces. Minor hepatic metabolism of candesartan occurs by O-deethylation to form an inactive metabolite.
Elimination: After oral administration: Renal 33%, Fecal (biliary) 67%.

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