Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

Key value for chemical safety assessment

Skin sensitisation

Endpoint conclusion
Endpoint conclusion:
adverse effect observed (sensitising)
Additional information:
Migrated from Short description of key information:
The skin sensitisation potential was initially assessed using read-across approach; however, the study results available were conflicting: considering the progression in the category, the extreme components of the category are considerd "non sensitizer" and "inconclusive for sensitisation", respectively. Therefore, the substance of interest (CAS 92045-41-5) was tested (LLNA test) in order to establish to which component of the category has to be considered more similar.
Based on experimental results, the substance causes skin sensitisation at estimed concentration of 81% so it has to be considered as weakly sensitizer.

Justification for classification or non-classification

According to Regulation 1272/2008 the substance has to be classified as category 1B skin sensitizer.

According to Directive 67/548/EEC the substance has to be classified as R43.