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Environmental fate & pathways

Bioaccumulation: aquatic / sediment

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Description of key information

No significant accumulation in organisms is expected as a result of the distribution coefficient of n-octanol/water (log Pow).
The bioconcentration factor was calculated by means of EPISuite (v4.11) using EPISuite default values. A log BCF value of 0.50 (BCF value of 3.16 L/kg ww) was calculated for 2,5-dihydrofuran.

Key value for chemical safety assessment

Additional information

QSAR-disclaimer

In Article 13 of Regulation (EC) No 1907/2006, it is laid down that information on intrinsic properties of substances may be generated by means other than tests, provided that the conditions set out in Annex XI (of the same Regulation) are met.

According to Annex XI of Regulation (EC) No 1907/2006 (Q)SAR results can be used if (1) the scientific validity of the (Q)SAR model has been established, (2) the substance falls within the applicability domain of the (Q)SAR model, (3) the results are adequate for the purpose of classification and labeling and/or risk assessment and (4) adequate and reliable documentation of the applied method is provided.

For the assessment of 2,5 -dihydrofuran (Q)SAR results were used for bioaccumulation potential.The criteria listed in Annex XI of Regulation (EC) No 1907/2006 are considered to be adequately fulfilled and therefore the endpoint(s) sufficiently covered and suitable for risk assessment.