1-fluoro-2-nitrobenzene

Vapour pressure

Administrative data

Endpoint:

vapour pressure

Type of information:

experimental study

Adequacy of study:

key study

Study period:

from 08 Sep 2005 to 26 Jan 2006

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Remarks:

GLP compliant

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2006

Report date:

2006

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

OECD Guideline 104 (Vapour Pressure Curve)

Version / remarks:

27 July 1995

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Remarks:

Certificate from 2005-11

Type of method:

dynamic method

Test material

Test material information

Constituent 1

Reference substance name:

1-fluoro-2-nitrobenzene

EC Number:

216-088-0

EC Name:

1-fluoro-2-nitrobenzene

Cas Number:

1493-27-2

Molecular formula:

C6H4FNO2

IUPAC Name:

1-fluoro-2-nitrobenzene

Test material form:

liquid

Details on test material:

Identity: 2-FLUORONITROBENZENE
CAS No.: 1493-27-2

Results and discussion

Vapour pressure

Key result

Temp.:

25 °C

Vapour pressure:

0.031 hPa

Remarks on result:

other: Mean of the values extrapolated at 25 °C in both experiments

Any other information on results incl. tables

First experiment

 

Boiling Temperature (°C)	Measured Pressure (hPa)
81	4
89	8
100	13
108	20
114	24
117	32
118	45
120	50
123	62
128	82
132	106
140	143

 

Ln P_vp(mbar) = b x 1/T (Kelvin) + a

Where:

b = slope = -8969.5

a = y-axis intercept = 26.66

r²= 0.9801

 

From this correlation, the vapour pressure was extrapolated at 25 °C to be equal to 3.22 Pa.

 

Second experiment

 

Boiling Temperature (°C)	Measured Pressure (hPa)
93	9
102	10
107	17
111	24
115	29
118	33
121	40
124	45
127	53
129	62
134	82
139	102
143	150

 

Ln P_vp(mbar) = b x 1/T (Kelvin) + a

Where:

b = slope = -8806.2

a = y-axis intercept = 26.03

r²= 0.9831

 

From this correlation, the vapour pressure was extrapolated at 25 °C to be equal to 2.96 Pa.

 

Remark

 

OECD test guideline 104 defines the dynamic method as being suitable for vapour pressures in the range of 10^3 (1000) to 10^5 (100000) Pa. Except two values in the first experiment and one in the second experiment, the measured pressures were thus in the applicability range of the method.

Applicant's summary and conclusion

Conclusions:

The vapour pressure of 2-fluoronitrobenzene is 3.09 Pa at 25°C.

Executive summary:

The vapour pressure of 2-fluoronitrobenzene was determined according to OECD guideline No. 104, using the dynamic method, and under GLP conditions. The test was carried out in duplicate. In the first experiment, 12 values were measured starting at 81 °C and stopping the heating at 140 °C. In the second experiment, 13 values were measured starting at 93 °C and stopping the heating at 143°C. In the first and second experiments, the vapour pressure was extrapolated at 25 °C to be equal to 3.22 and 2.96 Pa, respectively. The vapour pressure of 2-fluoronitrobenzene at 25°C was calculated as the mean from both experiments to be 3.09 Pa at 25°C.