Registration Dossier
Registration Dossier
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EC number: 203-336-8 | CAS number: 105-83-9
Acute Toxicity: other routes
Administrative data
- Endpoint:
- acute toxicity: other routes
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Study period:
- 1963
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: No GLP, no guideline followed, not enough data to complete a full IUCLID record.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 963
- Report date:
- 1963
Materials and methods
Test guideline
- Qualifier:
- no guideline available
- GLP compliance:
- no
- Limit test:
- yes
Test material
- Reference substance name:
- N,N-bis(3-aminopropyl)methylamine
- EC Number:
- 203-336-8
- EC Name:
- N,N-bis(3-aminopropyl)methylamine
- Cas Number:
- 105-83-9
- Molecular formula:
- C7H19N3
- IUPAC Name:
- bis(3-aminopropyl)(methyl)amine
- Details on test material:
- - Name of the test substance: Bis-(3-aminopropyl-9methylamine, no further data.
Constituent 1
Test animals
- Species:
- mouse
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Route of administration:
- intraperitoneal
- Vehicle:
- water
- Doses:
- The mice were applied with 21 5 solution of teh test substance
- No. of animals per sex per dose:
- No data
- Control animals:
- not specified
Results and discussion
Effect levelsopen allclose all
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- 90 other: mm³
- Based on:
- test mat.
- Remarks on result:
- other: Equivalent to 0.09 mL/kg bw, obtained in mice with pH 11 21 % test solution.
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- 450 other: mm³
- Remarks on result:
- other: quivalent to 0.45 mL/kg bw, obtained in mice with pH 7 21 % test solution
Any other information on results incl. tables
Symptoms observed: agitation, staggering, shortness of breath, cramps
In autopsy: following application of teh basic test substance solution, corrosion of the peritoneaum was observed.
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
