Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Environmental fate & pathways

Endpoint summary

Administrative data

Description of key information

Additional information

Read across from L-arginine to L-arginine-HCl is performed. The justification for read across is given in the endpoint summary of section 5 of the IUDLID-File as well as in the toxicokinetic statement in section 7.1 of the IUCLID-file.

L-arginine showed 100% degradation (HPLC) after 28 days in a study according to OECD 301C and therefore can be considered as readily biodegradable.

The supporting studies also indicate that L-arginine is readily biodegradable.

In accordance with Annex IX sections to 2 and section columns 2 simulation tests on the biodegradation in surface water or sediment as well as soil are not necessary due to the ready biodegradability of the substance.