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EC number: 500-038-2 | CAS number: 25322-68-3 1 - 4.5 moles ethoxylated
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Long-term toxicity to fish
Administrative data
Link to relevant study record(s)
- Endpoint:
- long-term toxicity to fish, other
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Remarks:
- experimental data from various test chemicals
- Justification for type of information:
- experimental data from various test chemicals
- Reason / purpose for cross-reference:
- read-across source
- Reason / purpose for cross-reference:
- read-across source
- Qualifier:
- according to guideline
- Guideline:
- other: Refer below principle
- Principles of method if other than guideline:
- 2:Prediction done using ECOSAR v.1.11 model
3:Data is from peer reviewed journal - GLP compliance:
- no
- Analytical monitoring:
- no
- Vehicle:
- not specified
- Test organisms (species):
- other: Fish, 2: guppy fish
- Test type:
- other: 2: flow-through, 3: Semi static
- Water media type:
- saltwater
- Remarks:
- 3: Fresh water
- Total exposure duration:
- 28 d
- Remarks on exposure duration:
- 3: 7 days
- Reference substance (positive control):
- not specified
- Key result
- Duration:
- 28 d
- Dose descriptor:
- NOEC
- Effect conc.:
- 13 671.586 mg/L
- Nominal / measured:
- estimated
- Conc. based on:
- test mat.
- Basis for effect:
- mortality
- Remarks on result:
- other: Other details not known
- Duration:
- 7 d
- Dose descriptor:
- LC50
- Effect conc.:
- 1 150 mg/L
- Nominal / measured:
- estimated
- Conc. based on:
- test mat.
- Basis for effect:
- mortality
- Validity criteria fulfilled:
- not specified
- Conclusions:
- Based on the results the NOEC range of test chemical was determined to be from 1150-13671.586 mg/L
- Executive summary:
Summarized result for the toxicity of test chemical were studied and mention as below:
Based on the EPI Suite ECOSAR version 1.11 predicted model, In 28 days long term fish toxicity i.e NOEC value was estimated to be 13671.586 mg/l on fish for on the basis of mortality effects.
Above study was supported by the second study. The long term effect of the test chemical was studied on guppy fish. the study was conducted was for the period of seven days in a semi static conditions. The median lethal concentration of the test chemical was determined as 1150 mg/L. Based on the CLP classification the test chemical cannot be classified.
Thus based on the above results, chemical consider to be nontoxic and not classified as per the CLP classification criteria.
Reference
Description of key information
Long term toxicity to fish:
Based on the EPI Suite ECOSAR version 1.11 predicted model, In 28 days long term fish toxicity i.e NOEC value was estimated to be 13671.586 mg/l on fish for on the basis of mortality effects.
Based on the NOEC value it can be concluded that the test chemical is toxic to fish at environmentally relevant concentrations and can be considered for classification criteria.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 13 671.586 mg/L
Additional information
Summarized result for the toxicity of test chemical were studied and mention as below:
Based on the EPI Suite ECOSAR version 1.11 predicted model, In 28 days long term fish toxicity i.e NOEC value was estimated to be 13671.586 mg/l on fish for on the basis of mortality effects.
Above study was supported by the second study. The long term effect of the test chemical was studied on guppy fish. the study was conducted was for the period of seven days in a semi static conditions. The median lethal concentration of the test chemical was determined as 1150 mg/L. Based on the CLP classification the test chemical cannot be classified.
Thus based on the above results, chemical consider to be nontoxic and not classified as per the CLP classification criteria.
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