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Based on its physico-chemical properties such as low water solubility (< 0.05 mg/L), low volatilization potential (VP < 0.001 Pa) and high log Koc (> 5), sediment and soil are expected to be the main targets for environmental distribution of Diisodecyl azelate (CAS 28472 -97-1). Indeed, the results from the Fugacity model presented in the US EPA’s HPV document for the Diester category (American Chemistry Council’s Aliphatic Esters Panel, U.S. EPA, 2003) show that once released into the environment Diisodecyl azelate (CAS 28472-87-1) will be mainly distributed among the sediment (66.6%) and soil (29.8%) compartment. The results from another Mackay calculation (Level I) are in line with these findings (sediment (50.1%) and soil (49.5%)). However, due to its ready biodegradability, the substance will not persist in these compartments.