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Physical & Chemical properties

Water solubility

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Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
Study initiation date - 15 February 1999; Experiment start date - 17 February 1999; Experiment end date - 17 February 1999; Study completion date - 02 March 1999.
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 105 (Water Solubility)
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
flask method
Specific details on test material used for the study:
The test article had the following physico-chemical properties:
Name: 40574/B
Batch no: WP 23/PP
Expiry date: 08 February 2006
Storage: At room temperature about 20 °C.
Water solubility:
>= 170 000 mg/L
Conc. based on:
test mat.
Temp.:
20 °C
Remarks on result:
other: pH not determined
Conclusions:
The water solubility of FAT 40574/B was found to be > 170 g/L. The test substance is very soluble (>10 g/L).
Executive summary:

The water solubility of the test substance was determined in a study conducted according to OECD Guideline 105 in a GLP-certified laboratory. Shake flask method was used for this purpose. The concentration of the test item in this solution was determined by VIS-spectroscopy. Based on the findings of this study, the water solubility of FAT 40574/B was found to be >170 g/L. The test substance is very soluble (>10 g/L).

Description of key information

The water solubility of the test substance was 170 g/L at 20 °C. A water solubility of 100 g/L is used in the assessment (maximum value for EUSES).

Key value for chemical safety assessment

Water solubility:
100 g/L
at the temperature of:
20 °C

Additional information

The water solubility of the test substance was determined in a study conducted according to OECD Guideline 105 in a GLP-certified laboratory. Shake flask method was used for this purpose. The concentration of the test item in this solution was determined by VIS-spectroscopy. Based on the findings of this study, the water solubility of FAT 40574/B was found to be >170 g/L. The test substance is very soluble (>10 g/L).