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Physical & Chemical properties

Water solubility

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Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: According to international guideline(s), GLP-compliant, performed in recognized contract research organization, no restrictions, fully adequate for assessment.
Qualifier:
according to
Guideline:
OECD Guideline 105 (Water Solubility)
Deviations:
yes
Remarks:
(measurement after 24h only; this deviation is regarded as negligible since, based on visual assessment in the pre-test, a higher solubility could not be reached)
Qualifier:
according to
Guideline:
EU Method A.6 (Water Solubility)
Deviations:
yes
Remarks:
(measurement after 24h only; this deviation is regarded as negligible since, based on visual assessment in the pre-test, a higher solubility could not be reached)
GLP compliance:
yes (incl. certificate)
Type of method:
flask method
Key result
Water solubility:
456.2 g/L
Conc. based on:
test mat.
Temp.:
20.1 °C
pH:
6.5

The aquatic solutions observed after equilibration were clear dense yellowish liquids. Based on visual assessment, more test material could not be dissolved or homogenized in the amount of water used in the test.

Conclusions:
Interpretation of results (migrated information): very soluble (> 10000 mg/L)
The water solubility of WS400402 is at least 456.2 g/L at 20 ± 1°C.

Description of key information

Commission Regulation (EC) No 440/2008, Part A, A.6 (2008 ); OECD Guideline No. 105 (1995)

Methods: flask method, analysis via TOC (NPOC-method)

Result: The water solubility of WS400402 is at least 456.2 g/L at 20 ± 1°C.

Key value for chemical safety assessment

Water solubility:
456.2 g/L
at the temperature of:
20.1 °C

Additional information