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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Environmental fate & pathways

Hydrolysis

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Administrative data

Link to relevant study record(s)

Description of key information

A new Key study was added to the dossier which shows that the substance can be considered as hydrolytically stabel at high pH (4 /  7 / 9).
The substance hydrolyses rapidly to it's monochloride at simulated gastric conditions (pH 1.2 / 37 °C / 30 seconds - 8 hours)
Quantitative 119Sn-NMR spectroscopy has been used as a valuable analytical tool to directly identify and quantify all organotin components, which are formed as a result of hydrolysis of the tested substance.

Key value for chemical safety assessment

Half-life for hydrolysis:
1 yr
at the temperature of:
25 °C

Additional information

The study showed that DBT-MPTD at pH 9, 7 and 4 can be considered hydrolytically stable. After 5 days at 50 °C less than 10% DBT-MPTD was hydrolyzed (t 0.5 25°C > 1 year).

Under the simulated gastric conditions (0.1 M HCl / pH 1.2 / 37 °C) DBT-MPTD was hydrolyzed to DBTC-MPTD, its monochloro ester.

It can be concluded that DBTC-MPTD is the only metabolite of DBT-MPTD that was formed in the simulated mammalian gastric environment. No DBTC was formed under the conditions of this study.

The previous key study, Butler & White (2010), as the study with the surrogate substance Dibutyltin bis(2-ethylhexlmercaptoacetate), DBTE, was disregarded since in the new key study no DBTC was formed, on which the Butler study is based.