Registration Dossier
Registration Dossier
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EC number: 284-461-5 | CAS number: 84896-44-6
Partition coefficient
Administrative data
Link to relevant study record(s)
Description of key information
The study was considered to be not technically feasible according to the information provided in the Walker & White, 2010 study due to rapid hydrolyses of the test subtsance, as demonstrated in a water solubility study.
Key value for chemical safety assessment
Additional information
In accordance with Annex XI section 2 of the Regulation EC 1907/2006, testing for a specific endpoint may be omitted, if it is technically not possible to conduct the study as a consequence of the properties of the substance.
The following statement was included in a physico-chemical properties study by Walker & White (2010) concerning the feasibility of a partition coefficient study on the test substance:
"No determination was performed according to Methods 107 and/or 117 of the OECD Guidelines for Testing of Chemicals, 27 July 1995 and 13 April 2004 respectively, for the following reasons:
• During preliminary investigations for the water solubility test, the test item was concluded to hydrolyse fully within 3 minutes of contact with water. Substances which hydrolyse rapidly in contact with water are not suitable for determination using Methods 107 and/or 117.
• Estimation using the ratio of the solubility of the test item in n-octanol and water would also be unreliable due to the rapid hydrolysis of the test item in the water."
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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