Registration Dossier
Registration Dossier
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EC number: 223-242-0 | CAS number: 3779-63-3
Endpoint summary
Administrative data
Key value for chemical safety assessment
Effects on fertility
Effect on fertility: via oral route
- Endpoint conclusion:
- no study available
Effect on fertility: via inhalation route
- Endpoint conclusion:
- no adverse effect observed
Effect on fertility: via dermal route
- Endpoint conclusion:
- no study available
Additional information
A data waiving is claimed for toxicity to reproduction for (2,4,6-trioxotriazine-1,3,5(2H,4H,6H)-triyl)tris(hexamethylene) isocyanate. A full and detailed text elaborating the data waiving is attached to this endpoint summary.
Justification for selection of Effect on fertility via inhalation route:
No study selected, since based on read-across two reproductive toxicity screenings are available, and both are considered relevant for assessment.
Effects on developmental toxicity
Effect on developmental toxicity: via oral route
- Endpoint conclusion:
- no study available
Effect on developmental toxicity: via inhalation route
- Endpoint conclusion:
- no adverse effect observed
Effect on developmental toxicity: via dermal route
- Endpoint conclusion:
- no study available
Additional information
A data waiving is claimed for developmental toxicity for (2,4,6-trioxotriazine-1,3,5(2H,4H,6H)-triyl)tris(hexamethylene) isocyanate. A full and detailed text elaborating the data waiving is attached to this endpoint summary.
Justification for selection of Effect on developmental toxicity: via inhalation route:
No study is selected, since three fully reliable developmental toxicity studies are available based on read across, and are all considered relevant for assessment.
Justification for classification or non-classification
No classification is required for toxicity to reproduction according to Regulation (EC) No 1272/2008, Annex I.
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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