Registration Dossier
Registration Dossier
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EC number: 200-861-4 | CAS number: 75-33-2
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
Description of key information
Propane-2-thiol was not readily biodegradable under conditions of the 28-day closed bottle test.
Key value for chemical safety assessment
- Biodegradation in water:
- under test conditions no biodegradation observed
- Type of water:
- freshwater
Additional information
L'Haridon (2003) study indicates that propane-2-thiol is not biodegradable under aerobic conditions when assessed in the frame of an OECD 301D test. At test termination, the biodegradation of the test substance was 0%. The replicate of 1.5 mg/L concentration of test substance could have obstructed the progress of the study as it may have been toxic to the inoculum. Potential degradation of the test item could be confirmed through further testing. This is considered a suitable study for this endpoint and the results are supported by a non-GLP, non-guideline published study. Van Leerdman (2006) demonstrated that during more than 100 days of incubation, no sulphide was formed from propane-2-thiol, which indicates that there was no degradation of the substance in any of the test samples under anaerobic conditions.
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