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Environmental fate & pathways

Adsorption / desorption

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Description of key information

Adsorption to solid soil phase is not expected.

Key value for chemical safety assessment

Additional information

Adsorption / desorption

Waiving argument

According to Annex IX of REACH, the study does not need to be conducted as the substance is readily biodegradable (please refer to IUCLID5, section 5.2.1). Nevertheless, calculation results are available.


Supporting model prediction

Using the calculation according to Franco & Trap the Koc and the log Koc were calculated at different relevant pH values. The pH corrected logKoc were calculated to be 3.08 at pH=5, 2.64 at pH=7 and 2.04 at pH=8 respectively.


In addition, the log Koc was estimated by KOCWIN (as part of EPISuite v4.11). Using the MCI method the log Koc and the Koc were calculated to be 1.7538 and 56.73 and using the logKow method the log Koc and the Koc were calculated to be 0.8933 and 7.821 respectively. All available data are in the same range and support the waiving argument. In conclusion it was stated that Adsorption to solid soil phase is not expected.



In Article 13 of Regulation (EC) No 1907/2006, it is laid down that information on intrinsic properties of substances may be generated by means other than tests, provided that the conditions set out in Annex XI (of the same Regulation) are met. Furthermore according to Article 25 of the same Regulation testing on vertebrate animals shall be undertaken only as a last resort.


According to Annex XI of Regulation (EC) No 1907/2006 (Q)SAR results can be used if (1) the scientific validity of the (Q)SAR model has been established, (2) the substance falls within the applicability domain of the (Q)SAR model, (3) the results are adequate for the purpose of classification and labelling and/or risk assessment and (4) adequate and reliable documentation of the applied method is provided.


For the assessment of 2-aminoethyldiethylamine (Q)SAR results were used for adsorption / desorption. The criteria listed in Annex XI of Regulation (EC) No 1907/2006 are considered to be adequately fulfilled and therefore the endpoint(s) sufficiently covered and suitable for risk assessment.


Therefore, further experimental studies on adsorption / desorption are not provided.