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Administrative data

toxicity to soil microorganisms
Type of information:
experimental study planned
Justification for type of information:
According to column 2 of annexe IX of REACh regulation EC 1907/2006 "In the absence of toxicity data for soil organisms, the equilibrium partitioning method may be applied to assess the hazard to soil organisms". The exposure assessment of DPTU (see Chapter 9 of the chemical safety report) based on PNECsoil(screen) does not indicate any risk for terrestrial compartment under any scenario (all RCRs to all compartments are below 1 and all the supported uses are therefore assessed to be safe)
However, in accordance with ECHA’s guidance on information requirements and chemical safety assessment, chapter R7c (v3.0 ; June 2017; pp. 154 -159), in the absence of data of toxicity to soil organisms for soil hazard category 3 substances as is the case for DPTU (Non Readily biodegradable substance classified as toxic to aquatic life with long lasting effets), confirmatory long-term terrestrial toxicity testing must be carried out. Therefore the registrant proposes to perform an OECD 216.
Short-term terrestrial toxicity testings are waived.

Data source

Materials and methods

Test guideline
according to guideline
OECD Guideline 216 (Soil Microorganisms: Nitrogen Transformation Test)

Test material

Constituent 1
Chemical structure
Reference substance name:
EC Number:
EC Name:
Cas Number:
Molecular formula:

Results and discussion

Applicant's summary and conclusion