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Administrative data

Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
24.04.2013 - 10.05.2013
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2013
Report date:
2013

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: shake-flask method
Principles of method if other than guideline:
Determination of ratio of concentrations of a compound in the two phases of a mixture of Octanol-Water at equilibrium
GLP compliance:
no
Type of method:
shake-flask method to: flask method
Partition coefficient type:
octanol-water

Test material

Constituent 1
Chemical structure
Reference substance name:
5-aminonaphthalene-2-sulphonic acid
EC Number:
204-351-2
EC Name:
5-aminonaphthalene-2-sulphonic acid
Cas Number:
119-79-9
Molecular formula:
C10H9NO3S
IUPAC Name:
5-aminonaphthalene-2-sulfonic acid
Test material form:
other: Amorphous
Details on test material:
- Name of test material: 5-aminonaphthalene-2-sulphonic acid
- Substance type: Organic
- Physical state: solid

Results and discussion

Partition coefficient
Type:
Pow
Partition coefficient:
0.91
Temp.:
39 °C
pH:
3.13
Remarks on result:
other: Log Pow = -0.04095
Details on results:
Converting the above Pow value into its Log value, the Log Pow of 5-aminonaphthalene-2-sulphonic acid is -0.04095 at temperature 39 deg C and pH of 3.13

Applicant's summary and conclusion

Conclusions:
The experimental value of octanol water partition co-efficient (log Pow) of of 5-aminonaphthalene-2-sulphonic acid by Shake flask method was found to be -0.04095 at temperature 39 deg C and pH of 3.13.This value indicates that 5-aminonaphthalene-2-sulphonic acid is hydrophilic in nature.
Executive summary:

The experimental value of octanol water partition co-efficient (log Pow) of of 5-aminonaphthalene-2-sulphonic acid by Shake flask method was found to be -0.04095 at temperature 39 deg C and pH of 3.13.This value indicates that 5-aminonaphthalene-2-sulphonic acid is hydrophilic in nature.