Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Link to relevant study record(s)

Description of key information

Key value for chemical safety assessment

Additional information

Alchisor CAL 145 comprises alkenes C13-14 hydroformylation products with read-across from the chemically-similar Alchisor CAL 123 as defined in the `Read-Across Justification Document'. Where toxicological data exist for Alchisor CAL 123, these are representative of the Alchisor CAL 145 substance.

Structural assessment


The substance is a complex UVCB which contains a variety of esters, alcohols, ethers and paraffins.


Different components and functional groups within these substances could undergo a variety of Phase I metabolism reactions, for example oxidation of alcohol groups to aldehydes and/or carboxylic acids, followed by Phase II conjugation reactions. The ester components might also undergo some degree of hydrolysis to the corresponding carboxylic acid and alcohol moieties.


The Molecular Weight of the component substances would indicate that some degree of absorption is possible. Furthermore any hydrolysis of the ester components will create lower MW species which would be more easily absorbed.




The substance is relatively poorly soluble in water (<1.2 mg/l). The Log Pow is 6. The high lipophilicity will tend to limit absorption.



The substance did not give rise to any signs of toxicity in any of the available toxicology studies at doses of up to 2000 mg/kg and hence provides no direct evidence regarding its toxicokinetic behaviour.



Based on the available structural data, phys-chem properties and toxicology data, it is likely that the substance is very poorly absorbed.