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EC number: 222-079-2 | CAS number: 3338-24-7
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Justification for type of information:
- Please refer to Read Across Statement attached in Section 13
- Reason / purpose for cross-reference:
- read-across source
- Key result
- Parameter:
- % degradation (O2 consumption)
- Value:
- 1.5
- Sampling time:
- 7 d
- Remarks on result:
- other: Test product
- Key result
- Parameter:
- % degradation (O2 consumption)
- Value:
- 1.3
- Sampling time:
- 14 d
- Remarks on result:
- other: Test product
- Key result
- Parameter:
- % degradation (O2 consumption)
- Value:
- 1.9
- Sampling time:
- 21 d
- Remarks on result:
- other: Test product
- Key result
- Parameter:
- % degradation (O2 consumption)
- Value:
- 0.4
- Sampling time:
- 28 d
- Remarks on result:
- other: Test product
- Key result
- Parameter:
- COD
- Value:
- 260 other: mg/l
- Results with reference substance:
- Activity control:
The oxygen consumption in the activity control showed that the activity of the inoculum was satisfactory. After 14 days, the biodegradation of sodium benzoate corresponded to 72.6 ±7.8% of ThOD.
Toxicity control:
Oxygen consumption to 30.6% of the ThOD was observed after 14 days in the toxicity controls. Therefore, the test product can be considered not inhibitory according to the guideline (OECD 301D). - Validity criteria fulfilled:
- yes
- Remarks:
- Oxygen consump. in inoculum control (28 d) = 0.56 mg O2/L (1.5 mg O2/L). Dif. between extreme replica at end of test = 4% (< 20%). BOD ref. sub.at 14 d = 72.6% of ThOD (> 60%). Test product not inhibitory to inoculum. Biodegra. = 30.6% of ThOD (> 25%)
- Interpretation of results:
- under test conditions no biodegradation observed
- Conclusions:
- test item was found to be not biodegradable under the test conditions within the 28-day exposure period.
Remark: the test solution contains NaOH due to the production method.
Due to the similarity of the target substance (EP1-Na) and the source substance (IBP1-Na) the result of this study is assessed to be adequate in order to fulfil the requirements of REACH. The read-across approach is further described in the document “Justification of read across from CAS No 53378-51-1 IBP1-Na (source) to CAS No 3338-24-7, EP1-Na (target)” attached in “Point 13 Assessment reports”. - Executive summary:
Test substance was tested in a concentration of 5.0 mg/l and reference substance in a concentration of 2.0 mg/l.
The substance was found to be not biodegradable under the test conditions within the 28-day exposure period.
The oxygen consumption in the activity control showed that the activity of the inoculum was satisfactory.
In the toxicity control containing both the test substance and the reference item sodium benzoate no inhibitory effect on microorganisms in inoculum was observed.
In the procedure controls the reference item sodium benzoate was readily biodegraded by an average of 72.6 % within 14 days of exposure; thus confirming suitability of the activated sludge
Due to similarities in structure it is expected that the target substance has the same properties.
Reference
Biodegradation of test substance and reference substance tested seperately and in combination. (average of triplicate values)
| Time(days) | Test product "Danafloat TM 245 (IBP1 -Na) (% of ThOD) | Activity control (sodium benzoate) (% of ThOD) | Toxicity control "DanafloatTM 245 (IBP1 -Na)" + sodium benzoate (% of ThOD) |
| Average | Average | Average | |
| 7 | 1.5 | 65.2 | 27.3 |
| 14 | 1.3 | 72.6 | 30.6 |
| 21 | 1.9 | 76.9 | 29.7 |
| 28 | 0.4 | 71.2 | 28.7 |
Description of key information
The source substance was found to be not biodegradable under the test conditions within the 28-day exposure period.
Remark: the test solution contains NaOH due to the production method.
Key value for chemical safety assessment
- Biodegradation in water:
- not biodegradable
- Type of water:
- freshwater
Additional information
In the toxicity control containing the source substance no inhibitory effect on microorganisms in inoculum was observed.
Due to the similarity of the target substance (EP1-Na) and the source substance (IBP1-Na) the result of this study is assessed to be adequate in order to fulfil the requirements of REACH. The read-across approach is further described in the document “Justification of read across from CAS No 53378-51-1 IBP1-Na (source) to CAS No 3338-24-7, EP1-Na (target)” attached in “Point 13 Assessment reports”.
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