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Environmental fate & pathways

Bioaccumulation: aquatic / sediment

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Administrative data

Endpoint:
bioaccumulation in aquatic species: fish
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: OECD-Guideline study with acceptable restrictions.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1984

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
OECD Guideline 305 C (Bioaccumulation: Test for the Degree of Bioconcentration in Fish)
Deviations:
yes
Remarks:
1.) concentration of test substance differed more than 20% of the mean of the measured values 2.) the lipid content of fish was only determined at the end of the test
GLP compliance:
yes

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
- Name of test material (as cited in study report): 1,2,4-Trichlorbenzol
- Analytical purity: 98,1 %
- Impurities (identity and concentrations): no data
Radiolabelling:
no

Test organisms

Test organisms (species):
Cyprinus carpio

Study design

Route of exposure:
aqueous
Test type:
flow-through
Water / sediment media type:
natural water: freshwater
Total exposure / uptake duration:
56 d

Test conditions

Nominal and measured concentrations:
theoretic concentration in test chamber [mg/l] measured concentration in test chamber [mg/l]
0 (control) 0
0,01 0,00365
0,1 0,04165

Results and discussion

Bioaccumulation factoropen allclose all
Type:
BCF
Value:
830
Basis:
whole body w.w.
Remarks on result:
other: Conc.in environment / dose:0,004 mg/l
Type:
BCF
Value:
805
Basis:
whole body w.w.
Remarks on result:
other: Conc.in environment / dose:0,04 mg/l
Type:
BCF
Value:
17 303
Basis:
total lipid content
Remarks on result:
other: Conc.in environment / dose:0,004 mg/l
Type:
BCF
Value:
16 779
Basis:
total lipid content
Remarks on result:
other: Conc.in environment / dose:0,04 mg/l

Any other information on results incl. tables

An increase of the BCF during the time could not be shown. The authors guess that steady-state was already reached within the first seven days of testing. The depuration phase was not studied.

Applicant's summary and conclusion