Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 212-476-9 | CAS number: 821-38-5
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Skin irritation / corrosion
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Eye irritation
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (irritating)
Respiratory irritation
Endpoint conclusion
- Endpoint conclusion:
- no study available
Additional information
Dodecanedioic acid did not show irritating effects in an acute dermal irritation study. Based on a read across among category members, Tetradecanedioic acid is not expected as well to have irritating effects on skin. An acute eye irritation study was performed on Tetradecanedioic acid showed moderate to important occular reactions but not totally reversible.
Effects on eye irritation: highly irritating
Justification for classification or non-classification
According to Dangerous Substances Directive, DSD (67/548/EC) and CLP regulation (1272/2008/EC), Tetradecanedioic acid does not require classification regarding skin irritation. However, taking into account the important and not fully reversible occular reactions, the substance will be classified Xi; R41 (risk of serious damage to eyes) according to DSD and "Eye Damage 1", H318 (Causes serious eye damage) according to CLP.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
