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Dissociation constant

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Description of key information

The dissociaten constant of the substance is pKa 1 =9.6 ± 0.1 and  pKa 2 =6.9 ± 0.1 at 20°C.

Key value for chemical safety assessment

Additional information

A GLP study was conducted in accordance with the OECD Guideline for the Testing of Chemicals 112.The dissociation constant was determined by potentiometric titration.

The measurement of the dissociation constant (pKa) of the test item at 20°C ± 1°C using a test item concentration of about 0.01 mol/l resulted in the following values at 20 °C (rounded mean values of a triple determination each): pKa 1 =9.6 ± 0.1; pKa 2 =6.9 ± 0.1