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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Endpoint summary

Administrative data

Description of key information

Additional information

Short-term ecotoxicity testing was conducted on C4 acrylate. Studies were designed to ensure exposure to the maximum possible dissolved concentration of C4 acrylate in test media. Results based on mean measured concentrations showed EC/LC50 values greater than 0.32 mg/L for Brachydanio rerio (zebra-fish, 96-hr mortality), greater than 0.34 mg/L for Pseudokirchneriella subcapitata (green algae, 72-hr growth inhibition), and 1.2 mg/L for Daphnia magna (water flea, 48-hr immobility).


C4 Acrylate is not completely soluble in water and based on laboratory studies, the solubility of C4 acrylate decreases with increased ionic content of the medium. In the fish and daphnia studies, water accommodated fractions (WAFs) were prepared at a loading rate of 5 mg/L. Resulting concentrations were considerably lower (0.40 and 0.42 mg/L at the start of the first and last renewal, respectively) in the fish WAFs despite the fact that the same medium was used as the Daphnia test. It is believed by the testing laboratory that the maximum solubility in this medium was reached in the zebra-fish study and that likely the higher concentrations in the Daphnia study were above the medium solubility although no undissolved test substance was visible. In the algae study, the measured concentrations of the WAFs decreased significantly after 24 hours and all concentrations were below the limit of detection (< 0.04 mg/L) after 72 hours of exposure. The highest test concentration (nominal: 5mg/L) incubated without algae showed a similar decrease. All aquatic toxicity studies were classified as reliable without restriction since all reasonable steps had been taken to keep the test substance in solution within the context of the method as published at the test date.