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The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Environmental fate & pathways

Biodegradation in water: screening tests

Administrative data

Endpoint:
biodegradation in water: ready biodegradability
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: Guideline study conducted in accordance with GLP.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2005
Report date:
2005

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 301 B (Ready Biodegradability: CO2 Evolution Test)
GLP compliance:
yes

Test material

Constituent 1
Chemical structure
Reference substance name:
Retinyl propionate
EC Number:
230-363-2
EC Name:
Retinyl propionate
Cas Number:
7069-42-3
Molecular formula:
C23H34O2
IUPAC Name:
retinyl propionate
Details on test material:
- Vitamin A-propionat, 2,5 Mio, unstabilisiert (retinol propionat)
- Purity: 95.9 w - %
- Batch No.: 00000777L0 PBG-Nr.10540158
- Water solubility: < 10 ug/l

Study design

Oxygen conditions:
aerobic
Inoculum or test system:
activated sludge, domestic (adaptation not specified)
Details on inoculum:
- Source of inoculum/activated sludge: Municipal activated sludge from the wastewater treatment plant, stored in laboratory wastewater treatment plant, which was fed with municipal sewage.
- Pretreatment: The sludge was washed and aerated for 48 hours and then added to the test vessels to obtain a sludge concentration of 30 mg/L dry substance.
Initial test substance concentrationopen allclose all
Initial conc.:
25 mg/L
Based on:
test mat.
Initial conc.:
20 mg/L
Based on:
other: TOC
Reference substance
Reference substance:
aniline
Remarks:
(20 mg/L TOC)

Results and discussion

% Degradation
Parameter:
% degradation (CO2 evolution)
Value:
40 - 50
Sampling time:
28 d
Details on results:
- The test substance is in this test partly or moderately biodegradable.

- Kinetic of test substance (in %):
= 1 after 3 days
= 10 after 7 days
= 27 after 14 days
= 36 after 21 days
= 45 after 28 days

BOD5 / COD results

Results with reference substance:
Kinetic of control substance (in %):
= 70 after 10 days
= 88 after 28 days

Applicant's summary and conclusion

Interpretation of results:
other: not readily biodegradable according to OECD criteria