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EC number: 304-780-6 | CAS number: 94279-36-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
Description of key information
Not readily biodegradable: 20.7 - 45% (CO2 evolution) in 28 days based on read across (EU method C.4-C)
Enhanced ultimately biodegradable: 71.4 - 78% (CO2 evolution) in 40 - 50 days based on read-across (EU method C.4-C)
Key value for chemical safety assessment
- Biodegradation in water:
- inherently biodegradable, fulfilling specific criteria
Additional information
Two studies for 2,4-Benzenetricarboxylic acid, tri-C9-11-alkyl esters (CAS No. 94279-36-4) are available. However, these studies are not appropriate to assess the biodegradability of 1,2,4-Benzenetricarboxylic acid, tri-C9-11-alkyl esters (CAS No. 94279-36-4), because (i) a product is tested and no further information about the tested substance is given, (ii) a method is used which substantially differ from current guidelines (CEC-L-33-T-82) and (iii) only a short abstract is available which makes it impossible to verify the reliability and accuracy of the provided test results.
The assessment was therefore based on studies conducted with the analogue substance 1,2,4-Benzenetricarboxylic acid, mixed decyl and octyl triesters (CAS No. 90218-76-1) as part of a read across approach, which is in accordance with Regulation (EC) No. 1907/2006. Annex XI, 1.5. For each specific endpoint the source substance(s) structurally closest to the target substance is/are chosen for read-across, with due regard to the requirements of adequacy of the available data. Structural similarities and similarities in properties and/or activities of the source and target substance are the basis of read-across. A detailed justification is provided in the technical dossier (see IUCLID Section 13). Please consider that the originally proposed category approach addressing all Polyfunctional acid esters (PFAE) aromatic is currently under revision and will finally result in an analogue approach for the registration. Therefore, two documents, the category justification and explanatory notes for the analogue approach are provided in Section 13.
For 1,2,4-Benzenetricarboxylic acid, mixed decyl and octyl triesters (CAS No. 90218-76-1) two ready biodegradability studies are available. Both GLP studies were performed according to EU method C.4-C. Initial test concentrations of 14.8 and 14.95 mg/L (TOC) were applied. Based on CO2 evolution mean degradation rates of 45% and 20.7% were observed after 28 days. Hence, the substance is not readily biodegradable according to OECD criteria. Nevertheless, the test duration was extended to 43 and 48 days, respectively, resulting in overall biodegradation rates of 71.4 - 78% in the enhanced ready biodegradation test.
Conclusion:
Based on the data above, 1,2,4-Benzenetricarboxylic acid, tri-C9-11-alkyl esters (CAS No. 94279-36-4) can be considered as not readily biodegradable according to OECD criteria. However, it could be demonstrated that the biodegradation continued beyond the 28 day test period, which resulted in a biodegradation rate above the pass level of > 60% (CO2 evolution) after a test period of 43 and 48 days, respectively. This indicates that the test substance is enhanced ultimately biodegradable according to the criteria described in Section R.7.9.4.1 of the "Guidance on information requirements and chemical safety assessment -Chapter R.7b: Endpoint specific guidance" (ECHA, 2017).
As the screening criteria for persistency listed in table R.11-2 of the “Guidance on information requirements and chemical safety assessment: Chapter R.11: PBT assessment (ECHA, 2017) are passed under the strict conditions of enhanced biodegradation tests, it can be concluded that the test substance is not persistent in the environment.
Due to the structural and property similarities with the tested category member 1,2,4-Benzenetricarboxylic acid, mixed decyl and octyl triesters (CAS No. 90218-76-1) the results are applicable to read across to 1,2,4-Benzenetricarboxylic acid, tri-C9-11-alkyl esters (CAS No. 94279-36-4).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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