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Short-term toxicity to aquatic invertebrates

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Description of key information

No immobility was observed in the 6.25, 12.5, 25 and 50 mg/l test concentrations over the 48-hour exposure period. In the 100 mg/l test concentration, no immobility was observed after 24 hours of exposure, and 25 % immobility was observed after 48 hours of exposure. 
Based on these results after 24 hours of exposure, the EC0 (NOEC) is ≥100 mg/l and the LOEC, EC50 and EC100 are >100 mg/l. After 48 hours of exposure, the EC0 (NOEC) is 50 mg/l, the LOEC is 100 mg/l, and the EC50 and EC100 are >100 mg/l.

Key value for chemical safety assessment

Additional information

The substance was tested for its acute toxicity to Daphnia magna over a period of 48 hours in a static system. The study was performed according to the OECD Guideline No. 202 Part I and the EEC Directive 92/69 C.2. The test method used for the conduct of this study is accredited according to EN 45001.

This test examined five nominal test article concentrations in the range from 6.25 to 100 mg/l over a test period of 48 hours.The test concentrations were spaced by a geometric progression factor of 2.0. Per concentration twenty daphnids (ten per replicate) were exposed to the test article. The actual test concentrations were determined analytically for three different test concentrations at the beginning and at the end of the 48-hour exposure period. Measured test article concentrations ranged from 97.8 to 107.7 % of nominal at the beginning, and from 84.1 to 107.8 % of nominal at the end of the test period. Based on these analytical results, the biological data are expressed as nominal concentrations of the substance.

5 % immobilization was observed in the control over the 48-hour exposure period. This occurrence is not significant and is within the accepted threshold of 10 % given by the OECD and EEC test guidelines for the control.

No immobility was observed in the 6.25, 12.5, 25 and 50 mg/l test concentrations over the 48-hour exposure period. In the 100 mg/l test concentration, no immobility was observed after 24 hours of exposure, and 25 % immobility was observed after 48 hours of exposure.

Based on these results after 24 hours of exposure, the EC0 (NOEC) is ≥100 mg/l and the LOEC, EC50 and EC100 are >100 mg/l. After 48 hours of exposure, the EC0 (NOEC) is 50 mg/l, the LOEC is 100 mg/l, and the EC50 and EC100 are >100 mg/l.