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EC number: 262-975-0 | CAS number: 61788-44-1
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to fish
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Justification for type of information:
- Data is from authoritative database
- Qualifier:
- according to guideline
- Guideline:
- other: Refer below principle
- Principles of method if other than guideline:
- Study was designed to assess the effect of test chemical on the mortality of fish.
- GLP compliance:
- not specified
- Analytical monitoring:
- no
- Vehicle:
- no
- Test organisms (species):
- other: Fish
- Test type:
- not specified
- Water media type:
- not specified
- Total exposure duration:
- 96 h
- Hardness:
- Not available
- Test temperature:
- Not available
- pH:
- Not available
- Dissolved oxygen:
- Not available
- Salinity:
- Not available
- Nominal and measured concentrations:
- Not available
- Details on test conditions:
- Not available
- Reference substance (positive control):
- not specified
- Key result
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- 5.6 mg/L
- Nominal / measured:
- meas. (not specified)
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Remarks on result:
- other: Other details not known
- Validity criteria fulfilled:
- not specified
- Conclusions:
- The lethal concentration (LC50) value of test chemical in fish in a 96 hr study on the basis of mortality effect was determine to be 5.6 mg/L.
- Executive summary:
Study was designed to assess the effect of test chemical on the mortality of fish. Test conducted for 96 hrs. The lethal concentration (LC50) value of test chemical in fish in a 96 hr study on the basis of mortality effect was determine to be 5.6 mg/L. The test chemical is highly insloluble in water the obtained LC50 value is much higher than the solubility of test chemical. Thus, by considering the solubility, test chemical cannot be toxic at its solubility limit.
Reference
Description of key information
Study was designed to assess the effect of test chemical on the mortality of fish. Test conducted for 96 hrs. The lethal concentration (LC50) value of test chemical in fish in a 96 hr study on the basis of mortality effect was determine to be 5.6 mg/L. The test chemical is highly insloluble in water the obtained LC50 value is much higher than the solubility of test chemical. Thus, by considering the solubility, test chemical cannot be toxic at its solubility limit.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 5.6 mg/L
Additional information
Data available for the test chemical from various sources, study has been reviewed to determine the short term toxicity on fish of the test chemical. The studies are as mentioned below:
Study was designed to assess the effect of test chemical on the mortality of fish. Test conducted for 96 hrs. The lethal concentration (LC50) value of test chemical in fish in a 96 hr study on the basis of mortality effect was determine to be 5.6 mg/L. The test chemical is highly insloluble in water the obtained LC50 value is much higher than the solubility of test chemical. Thus, by considering the solubility, test chemical cannot be toxic at its solubility limit.
Similar short term toxicity of test chemical were studied on the mortality of fish. The lethal concentration LC0, LC50 and LC 100 value of test chemical in fish (Brachydanio rerio) in a 96 hr study on mortality effect was determine to be 1,3.2 and 10 mg/L. The test chemical is highly insloluble in water the obtained LC50 value is much higher than the solubility of test chemical. Thus, by considering the solubility, test chemical cannot be toxic at its solubility limit.
Thus based on the above data available from various sources, chemical consider to be non toxic at its maximum solubility limit.
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